Hippocampal Polysynaptic Computation
نویسندگان
چکیده
منابع مشابه
Hippocampal polysynaptic computation.
Neural circuitry is a self-organizing arithmetic device that converts input to output and thereby remodels its computational algorithm to produce more desired output; however, experimental evidence regarding the mechanism by which information is modified and stored while propagating across polysynaptic networks is sparse. We used functional multineuron calcium imaging to monitor the spike outpu...
متن کاملBiophysics of Computation in Single Hippocampal Neurons
Biophysics of Computation in Single Hippocampal Neurons Anthony M. Zador Yale University 1993 In this thesis I examine the biophysical basis of computation in single neurons. I begin with the hypothesis that single neurons are more complex than the processing elements that comprise artificial neural networks, and that this complexity has some significance. My focus is on a cortical region calle...
متن کاملFunctional optical probing of the hippocampal trisynaptic circuit in vitro: network dynamics, filter properties, and polysynaptic induction of CA1 LTP
Decades of brain research have identified various parallel loops linking the hippocampus with neocortical areas, enabling the acquisition of spatial and episodic memories. Especially the hippocampal trisynaptic circuit [entorhinal cortex layer II → dentate gyrus (DG) → cornu ammonis (CA)-3 → CA1] was studied in great detail because of its seemingly simple connectivity and characteristic structu...
متن کاملPolysynaptic Excitatory Postsynaptic Potentials That Trigger Spasms
1 Polysynaptic excitatory postsynaptic potentials that trigger spasms 2 after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. 3 4 Katherine C. Murray, Marilee J. Stephens, Michelle Rank, Jessica D’Amico, 5 Monica A. Gorassini and David J. Bennett 6 Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada 7 8 9 Running Title: 5-HT1 receptors inhibit spas...
متن کاملState-dependent dendritic computation in hippocampal CA1 pyramidal neurons.
Depending on the behavioral state, hippocampal CA1 pyramidal neurons receive very distinct patterns of synaptic input and likewise produce very different output patterns. We have used simultaneous dendritic and somatic recordings and multisite glutamate uncaging to investigate the relationship between synaptic input pattern, the form of dendritic integration, and action potential output in CA1 ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2011
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1920-11.2011